Product Information

1.Chemical Structure

5 - ALA (5 - Aminolevulinic Acid) : Chemically known as 5 - aminolevulinic acid, it's an organic compound containing an amino group and a carboxyl group. There is an amino group and a carboxyl group in its molecular structure, and it's a non - cyclic amino acid. 

5 - ALA Hydrochloride : It's a salt formed by 5 - ALA and hydrochloric acid. Structurally, based on the 5 - ALA molecule, the amino group combines with the hydrogen ion of hydrochloric acid to form a positively

  charged ammonium - like structure. The formation of this salt changes the chemical properties of 5 - ALA, such as its solubility in water. 

5 - ALA Phosphate : It's a salt formed by 5 - ALA and phosphoric acid. The presence of the phosphate group makes the chemical structure of 5 - ALA phosphate different from both 5 - ALA and 5 - ALA hydrochloride. It contains a phosphate ion part, which also affects its physical and chemical properties.

2. Physical Properties 

Solubility

5 - ALA : It has a certain solubility in water, but it's relatively limited. Its solubility is affected by factors such as pH, and it may have different dissolution situations under acidic or alkaline conditions. 

5 - ALA Hydrochloride : Due to the formation of the hydrochloride, its solubility in water is usually better than that of 5 - ALA. Salt compounds can ionize in water to enhance their dissolution ability and are more easily dispersed in water to form a solution. 

5 - ALA Phosphate : It also has good water - solubility, and the phosphate part also contributes to its dissolution in water. Moreover, the presence of phosphate may make it perform better in some buffer systems. 

Stability

5 - ALA : It has relatively weak stability and may decompose or undergo chemical changes under some environmental conditions, such as high temperature, light, and acid - base environments.

 5 - ALA Hydrochloride: The formation of the hydrochloride improves the stability of the compound to a certain extent. For example, during storage, it's less likely to decompose due to external factors compared to 5 - ALA itself. 

5 - ALA Phosphate : Its stability is also enhanced. The phosphate ion binding to 5 - ALA can protect some active groups of the molecule, making it more stable under certain conditions. For example, in some micro - environments in organisms, 5 - ALA phosphate can better maintain its chemical integrity.

3. Chemical Properties 

Reactivity

5 - ALA : As a compound containing an amino group and a carboxyl group, it can undergo typical amino acid reactions, such as neutralization reactions with acids and bases, and condensation reactions with other compounds containing active groups. 

5 - ALA Hydrochloride : Since the amino group is protonated by hydrochloric acid, its reactivity is changed in some aspects. For example, its reactivity with bases is enhanced because it can undergo a hydrogen ion neutralization reaction. 

5 - ALA Phosphate: Its reactivity is mainly affected by both the phosphate group and the 5 - ALA part. The phosphate group can participate in some phosphorylation - related reactions, and the 5 - ALA part can still carry out its own amino acid reactions.

 Acid - Base Properties

 5 - ALA : It has amphoteric properties and can react with acids to exhibit basicity (the amino group accepts a proton) and can also react with bases to exhibit acidity (the carboxyl group donates a proton). 

5 - ALA Hydrochloride : It's generally acidic as a whole because it's formed by the combination of 5 - ALA and hydrochloric acid. In an aqueous solution, it ionizes to release chloride ions and protonated 5 - ALA, making the solution acidic. 

5 - ALA Phosphate: Its acid - base properties are quite complex. The presence of the phosphate group enables it to ionize to different degrees under different pH conditions, and the amphoteric properties of the 5 - ALA part will also jointly affect its behavior in acid - base environments. 

4. Application Fields 

Medical Field

5 - ALA : It has an important application in photodynamic therapy (PDT). It can be metabolized in the body to generate a photosensitive substance, which is used to treat certain cancers and skin diseases. For example, in the treatment of skin cancer, 5 - ALA is applied topically. After accumulating in the diseased cells, a photochemical reaction is triggered by light to destroy cancer cells. 

5 - ALA Hydrochloride: Its good water - solubility and stability give it an advantage in pharmaceutical formulations. In the development of some drugs that require intravenous injection or the preparation of oral liquid formulations, 5 - ALA hydrochloride may be a better choice. For example, in the development of drugs for the treatment of certain nervous system diseases, its physical and chemical properties are conducive to drug absorption and transportation. 

5 - ALA Phosphate : It's widely used in some cell culture and tissue engineering studies. Due to the importance of phosphate in organisms, 5 - ALA phosphate can be used as a carrier of nutrients or signaling molecules to promote cell growth and differentiation.

 Agricultural Field

5 - ALA : It can be used as a plant growth regulator to promote photosynthesis and chlorophyll synthesis in plants. For example, in agricultural production, the appropriate use of 5 - ALA can improve the yield and quality of crops. 

5 - ALA Hydrochloride : It has application prospects as a fertilizer additive. Its good solubility makes it easier to mix with other fertilizer components and is convenient for plants to absorb during irrigation or fertilization. 

5 - ALA Phosphate : In the development of some new - type fertilizers, 5 - ALA phosphate can combine the nutritional function of phosphorus and the physiological regulation function of 5 - ALA to provide comprehensive nutritional support for plants.