Liver Protection

What is N-Acetyl-L-cysteine

1. Chemical StructureIt's a derivative of cysteine. Cysteine is an amino acid containing a sulfhydryl group (-SH). N - Acetyl - L - cysteine has an acetyl group (-COCH₃) attached to the amino group (-NH₂) on the basis of cysteine. This structural modification leads to some differences in its chemical and physiological properties compared with cysteine.

2. Physical and Chemical Properties

Solubility: N - Acetyl - L - cysteine has good water - solubility. This property enables it to be conveniently used for preparing various pharmaceutical preparations or to be dissolved in aqueous systems as a reagent in biochemical experiments.

Stability: Due to the presence of the acetyl group, the chemical stability of cysteine is changed to a certain extent. It's relatively stable, but its chemical structure may change under extreme pH conditions or in the presence of certain specific enzymes.3. Physiological Functions and Applications

Antioxidant Effect    In organisms, it can act as an antioxidant. It scavenges excessive free radicals in the body through the sulfhydryl group in its molecule, such as hydroxyl radical (·OH) and peroxy radical (ROO·). Free radicals can damage biological macromolecules such as lipids, proteins and DNA of cells. N - Acetyl - L - cysteine can help reduce such damage and protect the normal structure and function of cells.

Mucolytic Effect     In the medical field, it's often used in the treatment of respiratory diseases. It can decompose the mucoprotein complex in mucus and reduce the viscosity of mucus. This makes it easier for patients to cough up phlegm, thus relieving the symptoms of airway obstruction. For example, it plays a role in the treatment of chronic bronchitis and emphysema.

Detoxification Effect     It has a detoxification effect on the poisoning of certain drugs and chemicals. For example, it can combine with the toxic metabolites produced by an overdose of acetaminophen (paracetamol) in the body and reduce the damage of these toxic metabolites to organs such as the liver, thus playing a crucial role in the rescue process of drug overdose poisoning.

COA  of N-Acetyl-L-cysteine

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