1、What is Liposome Delivery System?
As early as 1965, British scholars discovered that phospholipids can spontaneously form bilayer vesicles (micelles) in water and named them liposomes via electron microscopy. In other words, liposomes are bilayer structures spontaneously formed by lipid molecules or lipids in water. The common liposomes are generally made of phospholipids (amphiphilic) and cholesterol. Amphiphilic phospholipids form a bilayer structure, and cholesterol supports and maintains the bilayer structure.
2、Evolution of Liposomes
The development stages have evolved from early traditional phospholipids that were "plain" liposomes with water-soluble drugs, to antibody-targeted immunoliposomes, long-circulating liposomes grafted with protective polymers, as well as long-circulating immunoliposomes.
3、Function
Good Biocompatibility (good safety)
Can load both water-soluble and fat-soluble compounds
Has sustained release effect
Gastric juice pH 1-2; - Pepsin breaks proteins down into peptide chains
Small intestine: Intestinal juice pH @ about 8 - absorbs 90% of nutrients - phospholipid is a kind of fat, absorbed in the small intestine
High Bioavailability (1)
Significantly prolongs blood circulation (non-fasting conditions) (2)
4、Why Liposomes Is Popular in Dietary Supplements?
- Increased Bioavailability: Bioavailability refers to the amount of a nutrient or compound that is able to enter the body and have an active effect. Liposomal ingredients own a much higher bioavailability than traditional one, which means that a smaller dose can have a stronger impact.
- Improved Stability: Some nutrients are sensitive to heat, light, and humidity, which lead to break down or less effective. Liposomes can protect these sensitive compounds from degradation, making them more stable.
Overall, liposomal ingredients effectively deliver nutrients to the cells in your body. If you are interested in maximizing the effectiveness of your supplements, trying liposomal formulars.
5、What are the Common Liposomal Materials Offerings
Liposomal Glutathione
Liposomal Q10
Liposomal NMN
Liposomal NAD
Liposomal Vitamin C
Liposomal Resveratrol
Liposomal Berberine
Liposomal Silymarin
...
Natural Field has kept working on the R&D of new ingredients since 2005 and supply kinds of active ingredients solutions for different purposes, including Anti-Aging, Sports Nutrition, Liver Protection, Men’s Health.
6. Our Advantages
GMP System, Strict Quality Control All production processes are implemented in accordance with GMP rules. All Ingredients conform to Food grade with FSSC 22000, HACCP certificates.
Exclusive Technology Platform, supported by US PCT Patent, novel Liposome embracing Ginsenoside RG3. US PATENT No.: 20200369714 A1, 20170712920 A1, 10+ patents cover injection, tablet and capsule in pharmaceutical and food supplements;
Phospholipid sourced from 100% Sunflower, Non-GMO, Allergens Free.
Better Solubility, More uniform particle size distribution, range from 200nm ~ 700nm
True Liposome Encasulation, Not Simple Mixture.
7. References
1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151102/
2. https://www.sciencedirect.com/science/article/abs/pii/S0168365923006739
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