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Antioxidant test: Is Idebenone champion?

Q: What is Idebenone?

Idebenone is an organic compound with the molecular formula C19H30O5, which is yellow crystalline or crystalline powder and odorless. Very difficult to dissolve in water, very soluble in chloroform, methanol or absolute ethanol, soluble in ethyl acetate, difficult to dissolve in n-hexane.


When it comes to idobenzene, we have to talk about coenzyme Q10, Idobenzene is called (Hydroxydecyl Ubiquinone) on the ingredient list, and coenzyme Q10 is (Ubiquinone), from the name, we know that they are related.

So what’s the connection between CoQ10 and idebenone?

In fact, the molecular structure of idobenzene and coQ10 is similar, but the molecule is smaller than CoQ10 and is better absorbed; In addition, coenzyme Q10 has the opposite effect when external oxygen is insufficient. It accelerates the oxidation of the skin, and although idobenzene also oxidizes, it is relatively stable compared with coenzyme Q10.

Q: What are the benefits of idebenone?

1.Powerful antioxidant effect

In 2007, in a paper called Idebenone,green tea,and Coffeeberry extract: The article of new and innovative antioxidants quotes the results of a study on Idebenquinone and other antioxidants, and compares them with five comprehensive scores. The result is that Idebenquinone ranks first.


Idebenquinone can enter the mitochondria through the mitochondrial membrane to resist peroxide, improve its respiratory function, ensure the mitochondrial ETC to produce ATP, improve energy metabolism, resist the mitochondrial peroxide, protect the mitochondrial membrane, and reduce the production of peroxidase, thus inhibiting the generation of ROS.

In conclusion, idebenone is one of the antioxidants with excellent antioxidant properties, which can be confirmed by both in vitro experiments and clinical results.

2. Prevent dementia

Alzheimer’s disease is caused by the gradual increase of age and the degeneration of the central nervous system, resulting in changes in the disease. Patients may have various cognitive dysfunction such as memory loss and decreased responsiveness, which can be treated with drugs that improve blood supply to the brain and nourish the brain nerves.

Pharmacological studies have shown that:

Idbenquinone can now improve energy metabolism of brain cells and protect cell integrity and function.

Secondly, idebenone can reduce the damage of oxidative stress response to brain cells and protect the structure of brain cells.

Third, edbenquinone can promote blood vessel dilation and has an anti-platelet aggregation effect.

3. It can also be used in cosmetic formulations, with the efficacy of scavenging free radicals, inhibiting lipid peroxidation, inhibiting inflammation, inhibiting DNA damage, photoprotection, and reducing pigmentation.