What do the vitamins MK4 and MK7 refer to?Today we focus on the vitamins MK4 and MK7~
Sources and Classification of Vitamin K
There are two forms of vitamin K in our diet: vitamin K1 and K2.
Vitamin K1 is found mainly in green leafy vegetables or algae.
Vitamin K2 is the most biologically active form, with a longer half-life than vitamin K1, and is found mainly in foods of animal origin, such as liver or fermented foods such as yogurt, natto, or can be produced directly by human intestinal bacteria and can be subdivided according to the number of isoprene units (isoprene units) into MK-1 to MK-10, with MK-7 and MK-4 being the most common. MK-7 and MK-4 are the most common.
MK-7 is usually derived from natto, a popular Japanese food made from fermented soybeans. Compared to vitamin K1, long-term intake of MK-7 results in not only more stable levels in the blood, but also higher concentrations (up to 7 to 8 times higher) and significantly better distribution in various tissues.
MK-4, on the other hand, is found in animal tissues or, to a lesser extent, in meat and egg yolks.
Vitamin mk4 and mk7
Vitamin MK4 and Vitamin MK7 actually refer to a form of vitamin K known as menaquinone. Vitamin K is a fat-soluble vitamin that plays a vital role in the body, primarily in the blood clotting process. There are two main forms of vitamin K: vitamin K1 (phylloquinone) and vitamin K2 (menaquinone). Vitamin K2, in turn, includes several isoforms, of which MK4 and MK7 are the two common forms.
MK4 and MK7 differ slightly in their chemical structures, but they act similarly in the body. Both forms of vitamin K2 are known to promote bone health, maintain cardiovascular health, and support nervous system function. They help maintain normal bone mineralization by participating in the blood clotting process, as well as promoting cell growth and differentiation.
Can we take mk4 and mk7 together?
In supplements, MK4 and MK7 are often used together because they can complement each other functionally to provide more comprehensive vitamin K support. However, the need to use both MK4 and MK7 together, as well as the dosage to be used, should be determined based on an individual’s health status and needs.
Difference between mk4 and mk7
There are several key differences between MK4 and MK7 of vitamin K2.
♦First, they differ in chemical structure; MK4 and MK7 are two different isoforms of vitamin K2 with different side-chain lengths.MK4 has four isoprenoid units, whereas MK7 has seven isoprenoid units.
♦Secondly, they differ in their biological activity.MK4 functions primarily in the liver, whereas MK7 is able to reach and accumulate in tissues, especially in the bone and cardiovascular system.
In addition, MK4 and MK7 differ in their half-life and bioavailability in the human body; MK4 has a shorter half-life and lower bioavailability, while MK7 has a longer half-life and higher bioavailability. This means that MK7 remains in the body longer and is able to sustain its effects.
♦Finally, MK4 and MK7 also differ in their roles in promoting bone health and cardiovascular health; MK4 is primarily responsible for maintaining bone health, while MK7 is more effective in maintaining cardiovascular health; MK7 activates specific proteins in the heart and blood vessels that promote the deposition of calcium ions in the blood vessel walls, thereby inhibiting the abnormal deposition of calcium ions in the blood vessel walls, which can help to prevent the development of atherosclerosis. .
To summarize, there are significant differences between MK4 and MK7 in terms of chemical structure, biological activity, half-life, bioavailability, and effects.
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