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Citicoline:benefits and more

Do you know Citicoline?

Many people may not have heard of Citicoline, an intermediate in the synthesis of the cell membrane component phosphatidylcholine. It plays an important role in neuroprotection.

When it comes to Citicoline, the topic of memory comes up. As we age, almost everyone subjectively experiences some degree of memory loss, and Citicoline increases the amount of usable energy produced by the brain, which helps to improve concentration and focus. When our brains are energized, their ability to process information and store memories is enhanced!

It is clinically useful and is mainly used to treat a variety of neurodegenerative diseases such as Alzheimer’s disease, and some studies have also shown that cytarabine is able to increase the brain’s uptake of dopamine and glutamate, which improves cognitive performance.


What are the potential benefits of Citicoline?

1. The first is the effect of Citicoline on cells; Citicoline is a precursor for the synthesis of lecithin, a key component of cell membranes. Therefore, when given exogenously, Citicoline promotes lecithin biosynthesis, attenuates cell membrane damage, and repairs cell membrane structure. This property allows it to show potential in the treatment of diseases associated with cell membrane damage.

2.Citicoline has an important role in the brain. It has been used to improve the state of impaired consciousness and electroencephalogram after head trauma or brain surgery, and to promote the restoration of the function of upper limb utilization in hemiplegic patients with stroke. It has also shown efficacy in the treatment of acute pancreatitis, acute episodes of chronic recurrent pancreatitis, and postoperative acute pancreatitis when used in conjunction with proteolytic enzyme inhibitors.

3.Citicoline also increases norepinephrine and dopamine levels in the central nervous system, which may be related to its role in improving cognitive function. As a result, it has also been used to treat vascular, degenerative, and various causes of cognitive dysfunction.


3 methods of preparation of Citicoline

One is microbial fermentation

One is organic chemical synthesis method

And one is enzymatic synthesis

Is Citicoline safe?

The proposed scope and amount of use of cytarabine is safe as a new food ingredient. According to EFSA, cytarabine can be used in food supplements for middle-aged and elderly people at a maximum dosage of 500 mg/day and in foods for special nutritional purposes at a maximum dosage of 250 mg/serving; however, it is not suitable for children.

How long does it take for Citicoline to work?

Citicoline begins to work as soon as it enters the bloodstream, usually 15 – 30 minutes after consumption. Users may experience increased mental alertness, concentration and mental focus within this time frame. The full effects of Citicoline and cognitive enhancement will be experienced within the first 2 weeks of use with continued use and in conjunction with a proper diet and training program.


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