Fisetin: Anti-aging properties and potential for cellular longevity

Q: What is Fisetin?
Fisetin is a natural flavonoid antioxidant that belongs to the flavonol class of polyphenols. It is commonly found in various fruits and vegetables such as strawberries, apples, grapes, onions, and cucumbers. Fisetin is known for its potential health benefits, including its anti-inflammatory, neuroprotective, anticancer, and cardioprotective properties. It has also been studied for its potential in improving brain health and cognitive function. However, more research is still needed to fully understand the effects and benefits of fisetin.


Q: What foods rich in Fisetin?
Urushetin is found in many fruits and vegetables, such as strawberries, apples, persimmons, Onions and cucumbers. It can remove damaged senescent cells, improve health and extend service life, thus playing an effective anti-aging role.

Q: What are the benefits of Fisetin?
1. Antioxidant properties: Fisetin acts as a potent antioxidant, helping to neutralize harmful free radicals in the body, which can protect cells from oxidative stress and damage.

2. Anti-cancer potential: Fisetin has been studied for its potential in preventing and inhibiting the growth of cancer cells. It has shown promising results in various types of cancer, including breast, colon, lung, and prostate cancers.

3. Cardiovascular health: Fisetin may have protective effects on the cardiovascular system by reducing inflammation, improving blood vessel function, and preventing the buildup of plaques in the arteries. Anti-aging properties: Fisetin has been investigated for its potential anti-aging effects. It may activate specific pathways involved in longevity and cellular health.

4. Other potential benefits: Fisetin has also been studied for its potential in reducing pain, improving insulin sensitivity, and protecting against liver damage. It is important to note that while fisetin shows promise in various areas of research, further studies are needed, particularly in humans, to fully understand its effects and potential therapeutic applications.

Q: How does Fisetin work?
One of the key roles of urushetin is to initiate the so-called ERK pathway. ERK is short for “Extracellular signal-regulated kinase,” which means on the periphery of the cell, and kinase refers to a class of enzymes. So ERK is when something outside the cell sends a signal to the inside of the cell to activate the kinase.
By activating the ERK pathway, urushetin can optimize brain cell structure and function. This means it can help optimize cognition and memory. This effect has been repeatedly demonstrated in preclinical studies.

Q: What is the recommended dose of Fisetin?
There have only been two human studies of Fisetin, and both used a daily dose of 100 mg. Based on extensive animal data showing efficacy and safety, 5.6 mg is the most appropriate dose for humans and is based on U.S. Food and Drug Administration guidelines.