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Is Glutathione Good For The Skin?

What is Glutathione

Glutathione can purify the environment in the body, scavenge free radicals, delay skin aging, and also has a whitening effect!

It is a tripeptide composed of glutamic acid (Glu), cysteine (Cys), and glycine (Gly).

Glutathione plays an important role in the body’s biochemical defense system and has many physiological functions. It can not only eliminate free radicals in the human body, but also improve the immunity of the human body. Glutathione maintains health, resists aging, and can also protect hemoglobin from oxidation by hydrogen peroxide and free radicals, so that it can continue to perform its ability to transport oxygen normally.

Part of the hemoglobin in red blood cells is oxidized to ferric iron by hydrogen peroxide and other oxidants, which converts hemoglobin into methemoglobin, thereby losing the ability to carry oxygen. Reduced glutathione can directly combine with hydrogen peroxide and other oxidants to generate water and oxidized glutathione, and it can also reduce methemoglobin to hemoglobin. There is a lot of glutathione in human red blood cells, which is of great significance for protecting the sulfhydryl group of the protein on the red blood cell membrane in a reduced state and preventing hemolysis.


When the sun shines on the body, it triggers a series of chain reactions in which tyrosine is converted to dopa under the action of tyrosinase, which is the first decisive step in the synthesis of melanin. Tyrosine is an essential amino acid for physiological activities, and it exists in a large amount and extensively in the human body. The tyrosinase activity in darker-skinned skin is approximately three times that of lighter-skinned skin. If you want to control skin darkening, you can find ways to block the action of tyrosinase.

Since the amount of melanin synthesis is positively correlated with tyrosinase activity, blocking tyrosinase has become the key to preventing blackness. The ingredients that can inhibit the activity of tyrosinase include resveratrol, kojic acid, arbutin, azelaic acid, tranexamic acid, etc., with slightly different mechanisms of action.

The cysteine in glutathione has such a function. It has been found in medical tests that cysteine can reduce the activity of tyrosinase. Cysteine is an amino acid containing a sulfhydryl group. The sulfhydryl group has a strong nucleophilic effect. The sulfhydryl group can quickly react with dopaquinone to quickly form a colorless dopa derivative, thereby blocking the conversion of dopa to pigment.

What are the benefits of glutathione?

1) Skin (whitening, antioxidant):

Glutathione can prevents skin aging and pigmentation, reduces the formation of melanin, improves the skin’s antioxidant capacity, and makes the skin glow.

2) Weight loss:

Drinking glutathione can achieve the effect of slimming and whitening, general weight loss eats more vegetables and fruits, avoid frying greasy food, do not eat snacks do not eat too sweet things Guidance suggestions: participate in more physical exercise, running, fitness, swimming, etc. It is recommended not to use weight loss drugs to lose weight.

3)Protect the liver:

Glutathione helps reduce alanine aminotransferase (ALT, liver function index), attenuation parameter control (CAP, degree of liver fat accumulation), free fatty acids, and ferritin levels.

Is Glutathione Good For The Skin?

Glutathione has become increasingly popular in recent years for its potential benefits for the skin. It is a powerful antioxidant that is naturally produced by the body and helps to protect cells from damage caused by free radicals. While glutathione has been used for its health benefits internally, it has also shown promising results when applied topically to the skin.

Glutathione is known to help brighten and even out skin tone, which makes it a popular ingredient in many skin care products. It is also believed to reduce the appearance of dark spots and other age-related skin concerns. Additionally, glutathione has been shown to help protect the skin from harmful UV rays, which can cause premature aging and skin damage.

Aside from its aesthetic benefits, glutathione may also help to improve skin health in general. It has anti-inflammatory properties that can help to reduce acne and other skin irritations. It can also promote collagen production, which can help to keep the skin firm and youthful-looking.

Overall, glutathione is a promising ingredient for skin care. However, it is important to note that more research is needed to fully understand its potential benefits for the skin. As with any new skin care product, it is also important to patch test and discuss with a dermatologist before incorporating glutathione into your routine.