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Luteolin | 491-70-3 | anticancer potential

What do you know about luteolin?

structure               Luteolin
Molecular Weight 286.24 g/molComputed by PubChem 2.2(PubChem release 2021.10.14)
Description Luteolin, is a naturally occurring flavonoid compound. This compound is widely found in a variety of plants, such as carrots and lotus roots, and appears as yellow crystals.
Appearanc Light yellow fine powder

What are all the foods rich in luteoin?

Carrots, peppers, apples, oranges, chrysanthemums, etc.

Carrots and peppers

image from pexels.com

luteolin benefits for anti-cancer

luteolin is significantly helpful in the treatment of cancer.

luteolin exhibits its anti-cancer activity through multiple mechanisms. It can inhibit cell proliferation and angiogenesis in cancer cells by down-regulating key regulatory pathways associated with tumorigenesis, inducing oxidative stress, stalling the cell cycle and up-regulating apoptosis genes.

In addition, luteolin can also inhibit the activity of certain intracellular kinases, blocking the cell cycle and thus inhibiting the proliferation of tumor cells.

At the same time, the study also showed that luteolin can improve the cytotoxicity of certain anti-cancer drugs on tumor cells, which means it may be used as a potential cancer chemopreventive drug and chemotherapeutic drug to enhance the effect of traditional anti-cancer treatment.

An article published in BMC (biomedcentral) shows that luteolin has some positive impact on the treatment of cancer

study

BMC study

what other areas can luteolin be used in?

In addition to cancer treatment, luteolin has applications in several fields.

Luteolin also have certain antitussive and expectorant effects, so they are also commonly used in the treatment of chronic coughs and other symptoms, such as coughs caused by bronchial asthma and so on.

In addition, lignocaine, as a natural flavonoid, is also used in the fields of food additives, health products and cosmetics. In the field of pesticides, it can also be used as a growth regulator.

reference: https://cancerci.biomedcentral.com/articles/10.1186/s12935-022-02808-3

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