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luteolin supplement VS quercetin supplement

In the last post we compared luteolin to lutein, and in this post today we are comparing luteolin to quercetin in all aspects.

Luteolin and Quercetin are two common flavonoids that share some structural and functional similarities, but also some differences. The following is a comparison of them:

structure of them


structure of Quercetin

  1. Luteolin and Quercetin are both flavonoids with a C6-C3-C6 structure. However, they differ in the number and position of phenolic hydroxyl groups. Lignans have only one phenolic hydroxyl group at the 3-position, while quercetin has one phenolic hydroxyl group at each of the 3- and 4-positions. This structural difference causes them to differ in polarity, with luteolin being more polar than quercetin.
  2. Both Luteolin and Quercetin have biological activities such as anti-inflammatory, antioxidant, and antitumor. However, due to their structural differences, they may differ in specific aspects of their activities. For example, lignans may be more active in anti-inflammatory aspects, while quercetin may have more significant activity in antioxidant and anti-tumor aspects.

In addition, lignans have antibacterial and antiviral properties, while quercetin has benefits for cardiovascular health and immunomodulation. Both have potential applications in the prevention and treatment of a wide range of diseases, but the exact mechanism of action and effects may vary depending on the type of disease and individual differences.

Food Sources

Luteolin is mainly found in some herbs, vegetables and fruits, such as honeysuckle, chrysanthemum, celery, bell pepper, etc. Quercetin, on the other hand, is widely found in a wide range of fruits and vegetables, such as apples, onions and grapes.

To summarize, Luteolin and Quercetin are both flavonoids with similar biological activities, but with some differences in chemical structure, polarity, and specific mechanisms of action and effects. They also have different food sources and can be ingested in an appropriate manner based on individual needs and doctor’s recommendations. When using these compounds, you should follow your doctor’s instructions and pay close attention to any discomfort or suspected allergic reactions.

what are the similarities about luteolin and quercetin?

Luteolin and Quercetin are two flavonoids that have some similarities between them as described below:


Arthritic hands

  1. Antioxidant effects: Luteolin and Quercetin are both potent antioxidants that can scavenge free radicals from the body and protect cells from damage caused by oxidative stress. This antioxidant effect is important for the prevention and treatment of many diseases, such as cardiovascular disease and cancer.
  2. Anti-inflammatory effect: Both lignans and quercetin have anti-inflammatory activity, inhibiting the inflammatory response and the production of pro-inflammatory cytokines. This has potential therapeutic value in improving chronic inflammatory diseases such as arthritis and asthma.
  3. Anti-tumor effects: Both Luteolin and Quercetin have some anti-tumor activity, capable of inhibiting the growth and spread of tumor cells and inducing apoptosis. This has potential application value for the prevention and treatment of a variety of cancers.

In summary, Luteolin and Quercetin share some similarities in terms of chemical structure, antioxidant, anti-inflammatory, and anti-tumor effects, and food sources. These similarities make them both potentially applicable in the prevention and treatment of a wide range of diseases.


There are no specific recommended values or tolerable maximum intakes for quercetin. The dosage of quercetin varies greatly from 20mg/d to 2,000mg/d, and some studies have suggested that quercetin has some toxic side effects, but they are not significant.

The recommended dosage of each medical grade nutrient manufacturer is 100~600mg/d, but the absorption and utilization of medical grade patented products are very high, for example, the quercetin product that someone I know often use compared to the ordinary quercetin, which improves the absorption and utilization of quercetin by nearly 20 times.