NMN (nicotinamide mononucleotide) is an important intracellular molecule that has gained attention in recent years for its many benefits, including anti-aging, immune enhancement and improved health. This article will detail the BENEFITS of NMN to help you better understand this amazing molecule.
1.Anti-aging effect（The most important one）
NMN is the precursor of NAD+ (nicotinamide adenine dinucleotide) in the human body, and NAD+ is a necessary coenzyme for many important reactions in the human body. With age, the level of NAD+ in the human body gradually decreases, leading to cellular function decline and accelerating the aging process. Supplementation of NMN can increase the level of NAD+ in the body, thus slowing down aging and improving the health of the elderly.
🔔So is there any experiment that can prove this effect of NMN?
Yes, there is experimental evidence that NMN has an anti-aging effect. NMN is a precursor of NAD+. With age, the level of NAD+ in the body gradually decreases, leading to a decline in cellular function and accelerating the aging process. Supplementation of NMN can increase the level of NAD+ in the body, thus slowing down aging and improving the health of the elderly.
Image from pixabay.com
David Sinclair, a professor at Harvard University, was the first to discover the aging-delaying effects of NMN through experiments. In the experiment, David Sinclair injected NMN into 22-month-old rats, and one week later found that the physical functions of these rats were restored to the state of 6-month-old. Translated into human age, this equates to a reversal of physical state from 60 to 20 years old. In addition, the experiments also found that NMN supplementation can also improve the endurance and athletic ability of the mice, and reduce the effects of fatigue and stress on the mice.
In addition to animal experiments, there have been several human trials that have demonstrated the anti-aging effects of NMN. For example, a 12-week randomized, double-blind controlled trial showed that NMN supplementation significantly improved walking speed, sitting and standing ability, and balance in older adults, as well as improving their cognitive function and sleep quality.
Image from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238909/
2.Enhance immunity
NMN can enhance human immunity and improve resistance. Research has found that NMN can promote the proliferation and differentiation of immune cells, enhance the killing power and anti-inflammatory ability of immune cells, and effectively resist viral and bacterial infections.
3.Improve cardiovascular health
NMN has a cardiovascular protective effect, lowering blood pressure, lowering cholesterol and triglyceride levels, thus reducing the risk of heart disease and stroke.
NMN improves cardiovascular health in 2 main ways:
(1) Protecting the heart
NMN can promote the metabolism and repair of heart cells, reduce the burden on the heart, and at the same time, it can inhibit apoptosis and necrosis of heart cells, preventing the decline of heart function.
(2) Lowering blood pressure
NMN can inhibit the activity of angiotensin, thus lowering blood pressure, and at the same time, it can dilate blood vessels, increase vascular flow, and prevent cardiovascular diseases.
4.Improved Brain Function
NMN is beneficial for brain function, improving cognitive abilities such as memory, concentration and learning ability. It has been found that NMN promotes the proliferation and differentiation of nerve cells, protects them from oxidative damage, and improves symptoms of neurological disorders such as cognitive impairment and Alzheimer’s disease.
5.Improve sleep quality
NMN can improve sleep quality, increase sleep duration, and relieve problems such as insomnia and sleep disorders. Studies have found that NMN supplementation can regulate the body’s biological clock and promote the secretion of melatonin, thus improving sleep quality.
6.Protecting liver health
NMN has a protective effect on the liver, which can reduce the damage to the liver caused by alcohol and drugs, and reduce the risk of diseases such as fatty liver and cirrhosis.
