Spermidine is a naturally occurring polyamine with two or more amino groups, widely present in ribosomes and living cell tissues, and crucial for cell survival and function. It is converted from arginine as a precursor.
How we get Spermidine?
The biosynthesis process of spermidine begins with arginine, an amino acid that is gradually converted into spermidine through a series of reactions. Arginine first reacts with glutamine synthase to produce an intermediate product called N-glutamine arginine. Then, N-glutamine arginine reacts with linolenic acid dehydrogenase to produce linolenic acid cysteine. Linolenic acid cysteine then reacts with spermidine synthase, ultimately producing spermidine.
What are the benefits of Spermidine?
The main benefits of spermidine include the following:
1. Prolonging life
Spermidine is a natural antioxidant that helps extend life by scavenging reactive oxygen species and free radicals and protecting cells from oxidative damage.
2.Promote cardiovascular health
Spermidine can promote cardiovascular health because of its antioxidant and anti-inflammatory effects, which can reduce the risk of atherosclerosis and cardiovascular disease.
Spermidine can enhance the function of the immune system, improve the body’s resistance, and prevent infections and diseases.
4.Boost neurological function
Spermidine can boost the function of the nervous system because it promotes the growth and survival of neurons and improves memory and cognitive function.
5.Promote muscle growth
Spermidine can promote muscle growth and repair because it stimulates the proliferation and differentiation of muscle cells.
In conclusion, spermidine is a natural molecule with multiple benefits and a wide range of biological activities. However, it is important to note that while spermidine has many benefits, it does not mean that all people need to take spermidine supplements. For most people, spermidine needs can be met through a healthy diet and lifestyle.
Spermidine for anti-aging
The most prominent and important benefit of spermidine is its role in anti-aging. In recent years, more and more studies have shown that spermidine can delay the aging process of the body. It achieves this through a variety of pathways, including scavenging reactive oxygen species and free radicals, protecting cells from oxidative damage, extending life span, improving cardiovascular and nervous system function, and boosting immunity.
During aging, cells experience problems such as mitochondrial dysfunction and protein aggregation, leading to cell death and decreased tissue function. Spermidine can maintain mitochondrial protein abundance, protect its normal function, and promote protein degradation and autophagy, thereby maintaining cell health. In addition, spermidine can also regulate translation and proteomic characteristics by promoting the efficient translation extension of certain mrnas, further protecting cells from the damage of aging.
Safe and side effect:
Is spermidine safe?
Yes. The data suggest that spermidine supplementation using a food-extracted spermidine supplement is safe and well-tolerated.
Where to buy spermidine?
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