Adipose tissue is multifunctional and plays an important role in systemic energy homeostasis, but obesity has become a major risk factor for metabolic diseases. Dihydromyricetin plays an important role in preventing diet-induced weight gain and improving lipid accumulation in the liver.
Dihydromyricetin DHM is the most biologically active component of Garcinia Cambogia. Some studies claim that DHM has anti-adipogenic effects in adipocytes. Recent studies have shown that DHM reduces body weight and improves glycolipid metabolism disorders in obese mice; in addition, DHM stimulates the formation of beige fat in white adipose and primary adipocytes, and increases energy expenditure by activating the IRF4/PGC-1α signaling pathway.
study stem from https://pubmed.ncbi.nlm.nih.gov/35690863/
I. What is dihydromyricetin?
Dihydromyricetin, also known as prunetin, is a flavonoid extracted from plants of the genus Serpentine in the family Vitis vinifera. It has a variety of biological activities, such as antioxidant, anti-inflammatory, antialcoholic, hepatoprotective and so on. In recent years, studies have found that dihydromyricetin also has a potential weight loss effect, bringing new hope to the field of weight loss.
The relationship between dihydromyricetin and weight loss
- Regulation of fat metabolism
It is found that dihydromyricetin can regulate fat metabolism and inhibit the proliferation and differentiation of fat cells, thus reducing the accumulation of fat in the body. In addition, it also promotes the oxidation and decomposition of fatty acids, accelerating the consumption of fat and helping to reduce body weight and body fat content.
- Appetite Suppression
Dihydromyricetin has some appetite suppressant properties that can reduce food intake, thus helping to control body weight. Studies have shown that it can reduce the excitability of the appetite center by affecting the secretion of neurotransmitters and hormones, thus reducing appetite and the amount of food consumed.
- Improve intestinal microecology
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Gut microecology is closely related to weight loss. Research has found that dihydromyricetin can improve intestinal microecology, increase the number and diversity of beneficial bacteria and reduce the reproduction of harmful bacteria. This helps to promote intestinal peristalsis and defecation, reducing intestinal absorption of fat and sugar, thus contributing to weight loss.
Third, dihydromyricetin weight loss precautions
Although dihydromyricetin has a certain effect on weight loss, it is not effective for everyone. Each person’s physical condition and reaction are different, and the weight loss effect will also vary. In addition, dihydromyricetin, as a drug or health supplement ingredient, has certain adverse reactions and side effects. Therefore, when using dihydromyricetin for weight loss, you need to pay attention to the following points:
- Follow your doctor’s advice
Before using dihydromyricetin for weight loss, it is recommended to consult a professional doctor or pharmacist about your health condition and suitable dosage. Meanwhile, follow the advice of your doctor or pharmacist and take it according to the prescribed dosage and time to ensure the effectiveness and safety of the drug.
- Reasonable diet and exercise
Weight loss does not only rely on drugs or supplements, but also requires sensible diet and exercise. When using Dihydromyricetin for weight loss, you should pay attention to a healthy and balanced diet and reduce the intake of high-calorie and high-fat food. At the same time, increasing the amount of exercise and raising the body’s metabolic rate will help accelerate the weight loss effect.
- Be aware of adverse reactions
Although Dihydromyricetin is relatively safe, some adverse reactions may still occur, such as gastrointestinal discomfort and allergic reactions. If you experience any discomfort during use, you should stop the medication and consult your doctor.
