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What are ergothioneine skin benefits?

Ergothioneine skin benefits

(1) Whitening

Ergothioneine is a natural antioxidant that is highly protective of cells, non-toxic, and is not easily oxidized in water, which allows their concentration in some tissues to reach 7mmol-L and activates the cell’s natural antioxidant defense system. Research results show that the amount of ergothione added to cosmetics reaches 0.01%-0.03%, which can hinder pigment formation and deposit, and whiten the skin.


(2) Antioxidant: highly effective antioxidant, anti-aging.

L ‘Oreal has proposed that ergothioneine and its derivatives have the effect of reducing or even preventing protein glycosylation, thereby preventing age-related loss of skin elasticity, modifying and improving facial contours, and preventing or improving the appearance of orange skin lines.


(3) Suncare


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In the ultraviolet absorption range, ergothionein has a similar absorption wavelength to DNA, which can minimize the formation of reactive oxygen species and protect cells from radiation damage, so ergothionein can be used as a physiological filter of ultraviolet light. Many studies have shown that ergothione can avoid the damage of ultraviolet radiation on the skin, and is a very effective sunscreen ingredient.


(4) Anti-inflammatory, acne

Inflammation is the body’s response to an infection of the skin, and excessive UV exposure and stress are all causes of inflammation. Studies have shown that ergothione has an anti-inflammatory effect in skin cells, and it is even more effective when combined with vitamin C. Elizabeth Arden has done the application experiment of ergothione on the repair effect of UV-induced skin inflammation, showing that the combination of idobenzene and ergothione can reduce the skin inflammation and light damage caused by UV.


other benefits

(5) Synergy

Ergothione can regulate the REDOX reaction in the cell, participate in the regulation of energy in the cell, is the physiological protection agent of the cell, biological and pharmacological properties and its safety and stability. Therefore, adding ergothionein to a product can not only maintain the stability of other ingredients, but also promote the absorption of active ingredients by cells, which has a good synergistic effect, effectively enhance the efficacy of other ingredients, and achieve the effect of 1+1>2. For example: the use of ergothionein in an antioxidant product, not only can it play a strong antioxidant effect on its own, but also can cooperate with other antioxidants to strengthen its vitality.


(6) Organ transplantation:

The amount of tissue available and the duration of preservation play a decisive role in the success of organ transplantation. The most commonly used antioxidant for organ transplant preservation is glutathione, which is easily oxidized when exposed to the environment, even when refrigerated or in a liquid environment, its antioxidant capacity is greatly reduced, causing cell toxicity and inflammation, inducing hydrolysis of tissue proteins. Because ergothione is stable in aqueous solution and can chelate heavy metal ions as an antioxidant, it can be used as a substitute for glutathione in the field of organ protection to better protect transplanted organs.

🔔 Does it has side effects?

As a natural compound, ergothioneine has relatively few side effects, but there are still some issues to be aware of.

The main side effects include:

  1. Gastrointestinal discomfort: ergothioneine may cause some irritation to the gastrointestinal tract, leading to nausea, vomiting, diarrhea, and other uncomfortable symptoms. Therefore, when using Ergothioneine, it is recommended to follow medical advice and observe your own body reaction.
  2. Allergic reaction: For people with allergies, the use of Ergothioneine may cause allergic reactions, such as itching, redness and swelling of the skin, and difficulty in breathing. If allergic symptoms occur, discontinue use immediately and seek medical advice.
  3. Drug interactions: Ergothioneine may interact with certain medications, resulting in increased or decreased effectiveness. Therefore, if you need to use other drugs at the same time during the use of ergothioneine, please consult your doctor or pharmacist for advice.